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产品中心 药物靶点和Fc受体 药物靶点

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CD6 His Tag Protein, Human

TP120,T12

价格 ￥980.00 （ 供应商现货 ： 3-5个工作日）
货号 UA011258
规格
数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    TP120, T12

  • Accession

    P30203

  • 表达序列

    His18 - Glu398 with His Tag at C-terminus

  • 表达宿主

    HEK293

  • 分子量

    80-95 kDa（reducing）

  • 纯度

    >95% by SDS-PAGE & > 90% by SEC-HPLC

  • 内毒素含量

    <1EU/μg

  • 活性

    Immobilized CD6 His Tag Protein, Human (Cat. No. UA011258) at 5.0μg/mL (100μL/well) can bind ALCAM/CD166 Fc Chimera Protein, Human with EC50 of 2.95-3.49 ng/mL.

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS PH7.4 5% trehalose

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    Wang X, Zhang Y, Xu X, Liu X, Zhang B. Causal relationship between circulating cytokines and myelodysplastic syndrome: a Mendelian randomization study. Hematology.2025Dec;30(1):2541447. Li Z, Jia L, Huai S. Circulating Inflammatory Proteins Mediate the Causal Effect of Gut Microbiota on Inflammatory Bowel Disease: Bayesian and Mediated Mendelian Randomization. FASEB Bioadv. 2025 Jul 10;7(7):e70039.

背景介绍

  • CD6 (Cluster of Differentiation 6) is a cell-surface glycoprotein of the scavenger receptor cysteine-rich superfamily that acts as both a costimulatory molecule and an adhesion receptor during T-cell activation. It is expressed on thymocytes, mature T cells, B-1 B cells, and certain brain cells, and anti-CD6 monoclonal antibodies can enhance T-cell proliferation when combined with accessory cells, PMA, or anti-CD2 mAb.

  • 电泳

    • 2μg (R: reducing condition).

  • 体积排阻色谱(SEC-HPLC)

    • The purity of CD6 His Tag Protein, Human is greater than 90% as determined by SEC-HPLC.

  • ELISA

    • Immobilized CD6 His Tag Protein, Human (Cat. No. UA011258) at 5.0μg/mL (100μL/well) can bind ALCAM/CD166 Fc Chimera Protein, Human with EC50 of 2.95-3.49 ng/mL.

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