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产品中心 药物靶点和Fc受体 药物靶点

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Cyclophilin A GST Tag Protein, Human

Peptidyl-prolyl cis-trans isomerase A,PPIase A,Cyclosporin A-binding protein,Rotamase A

价格 ￥1,050.00 （ 供应商现货 ： 3-5个工作日）
货号 UA011249
规格
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    Peptidyl-prolyl cis-trans isomerase A, PPIase A, Cyclosporin A-binding protein, Rotamase A

  • Accession

    P62937

  • 表达序列

    Met1-Glu165, with GST Tag at the N-terminal

  • 表达宿主

    E.coli

  • 分子量

    43.5 kDa

  • 纯度

  • 内毒素含量

    <0.1EU/μg

  • 标记

    Unconjugated

  • 标签

    GST Tag

  • 缓冲体系

    1*PBS，PH7.4

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    1. Cell Death Dis. 2013 Oct 31;4(10):e888.
    2. Biochemistry (Mosc). 2022 Mar;87(3):259-268.

背景介绍

  • Cyclophilin A (CyPA, 18 kDa) is a ubiquitously distributed protein belonging to the immunophilin family. Cyclophilin A (CyPA) is a peptidyl-prolyl cis-trans isomerase that exists in the intracellular and secretory forms and has multiple functions. Intracellular CypA takes part in folding, transport, and assembly of proteins; regulates cell proliferation; is a ligand for cyclosporine A (CsA), mediating its immune-suppressive activity; mediates signal transduction from a T cell receptor, and controls the balance of T helpers 1 and 2, inhibiting activity of T helpers 2.

  • 电泳

    • 1μg (R: reducing condition, N: non-reducing condition).

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