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产品中心 药物靶点和Fc受体 药物靶点

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α-synuclein His tag Protein, Human

alpha-synuclein,Non-A beta component of AD amyloid,Non-A4 component of amyloid precursor (NACP),SNCA,NACP,PARK1

价格 ￥500.00 （ 1-2周）
货号 UA011215
规格
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    alpha-synuclein;Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor (NACP); SNCA; NACP; PARK1;

  • Accession

    P37840

  • 表达序列

    Met1-Ala140, with C-10*His

  • 表达宿主

    E.coli

  • 分子量

    Theoretical: 16.1kDa Actual: 20kDa

  • 纯度

    >95% by SDS-PAGE

  • 内毒素含量

    <1EU/μg

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, pH7.4.

  • 溶解方法

    Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.

  • 储存条件

    • 12 months from date of receipt, -20 to -70 °C as supplied.
    • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
    • 1 week, 2 to 8 °C under sterile conditions after reconstitution.
    • Please avoid repeated freeze-thaw cycles.


背景介绍

  • Alpha-synuclein is a neuronal protein that regulates synaptic vesicle trafficking and subsequent neurotransmitter release. It is abundant in the brain, while smaller amounts are found in the heart, muscle and other tissues. In the brain, alpha-synuclein is found mainly in the axon terminals of presynaptic neurons. Within these terminals, alpha-synuclein interacts with phospholipids and proteins. It plays a role in restricting the mobility of synaptic vesicles, consequently attenuating synaptic vesicle recycling and neurotransmitter release.

  • 电泳

    • 2μg (R: reducing conditions)

  • ELISA

    • Immobilized α-synuclein His tag Protein, Human at 2 μg/mL (50 μL/well) can bind α-Synuclein Recombinant Rabbit mAb (S-441-86) (S0B0344) with EC50 of 13.11-21.33 ng/ml.

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