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产品中心 药物靶点和Fc受体 药物靶点

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TACI/CD267/TNFRSF13B His Tag Protein, Human

CVID,CVID2,FLJ39942,MGC133214,ACIMGC39952,TNFRSF13B

价格 ￥1,200.00 （ 供应商现货 ： 3-5个工作日）
货号 UA011174
规格
数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    CVID; CVID2; FLJ39942; MGC133214; ACIMGC39952; TNFRSF13B

  • Accession

    O14836-1

  • 表达序列

    Ser2-Thr166 with His Tag at the C-terminus

  • 表达宿主

    HEK293

  • 分子量

    19-22kDa (Reducing)

  • 纯度

    ＞95% by SDS-PAGE & RP-HPLC

  • 内毒素含量

    <0.1EU/μg

  • 活性

    Immobilized BAFF Protein, Human (Cat. No. UA040367) at 1.0μg/mL (100μL/well) can bind TACI/CD267/TNFRSF13B His Tag Protein, Human (Cat. No. UA011174) with EC50 of 2.07-3.92ng/mL.

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, PH7.4,5% trehalose

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    von Bulow, G.U. et al. (1997) Science, 278:138.
    Marsters, S.A. et al. (2000) Curr. Biol. 10:785.

背景介绍

  • TACI (Transmembrane activator and CAML interactor) is a type III transmembrane protein and a member of the TNF receptor superfamily. It consists of an extracellular domain containing two cysteine-rich regions, a transmembrane domain, and an intracellular domain. TACI shares high homology with BCMA and binds to APRIL and BAFF, key ligands involved in immune regulation. Expressed on B cells and activated T cells, TACI plays a crucial role in B cell development and function. Its interactions with APRIL and BAFF suggest involvement in immune signaling pathways, making it a potential target for immunotherapy.

  • 电泳

    • 1μg (R: reducing condition, N:non-reducing condition).

  • ELISA

    • Immobilized BAFF Protein, Human (Cat. No. UA040367) at 1.0μg/mL (100μL/well) can bind TACI/CD267/TNFRSF13B His Tag Protein, Human (Cat. No. UA011174) with EC50 of 2.07-3.92ng/mL.

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