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TIM1/HAVCR1 His Tag Protein, Human

CD365,HAVCR1,HAVCR-1,HAVCRT cell immunoglobin domain and mucin domain protein 1,hepatitis A virus cellular receptor 1,Kidney injury molecule 1,KIM1,KIM-1,T-cell immunoglobulin and mucin domain-containing protein 1,TIM1,TIM-1,TIM-1TIM,TIM1TIMD-1,TIMD1T-cell membrane protein 1

价格 ￥1,280.00 （ 供应商现货 ： 3-5个工作日）
货号 UA011163
规格
数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    CD365; HAVCR1; HAVCR-1; HAVCRT cell immunoglobin domain and mucin domain protein 1; hepatitis A virus cellular receptor 1; Kidney injury molecule 1; KIM1; KIM-1; T-cell immunoglobulin and mucin domain-containing protein 1; TIM1; TIM-1; TIM-1TIM; TIM1TIMD-1; TIMD1T-cell membrane protein 1

  • Accession

    Q96D42

  • 表达序列

    Ser21-Gly295 with His Tag at C-Terminus

  • 表达宿主

    HEK293

  • 分子量

    72-95kDa (Reducing)

  • 纯度

    > 95% by SDS-PAGE & SEC-HPLC

  • 内毒素含量

    <0.1EU/μg

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, 5% trehalose, PH7.4

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    1.Meyers, J.H. et al. (2005) Trends Mol. Med. 11:1471.
    2.Kuchroo, V.K. et al. (2003) Nat. Rev. Immunol. 3:454.
    3.Mariat, C. et al. (2005) Phil. Trans. R. Soc. B 360:1681.

背景介绍

  • HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) or T cell immunoglobulin mucin 1 (TIM-1), is an integral membrane glycoprotein. KIM-1 is widely expressed, with the highest levels found in the kidney and testis. It is recognized as a major susceptibility gene for asthma, allergy, and autoimmunity in humans. IgA1lambda, a specific ligand of KIM-1, has been shown to have a synergistic effect in virus-receptor interactions. KIM-1 is implicated in the pathogenesis of acute kidney injury and has been confirmed as a biomarker of renal dysfunction in human urine. Additionally, KIM-1 is a novel regulatory molecule of flow-induced calcium signaling

  • 电泳

    • 1μg (R: reducing condition, N: non-reducing condition).

  • 体积排阻色谱(SEC-HPLC)

    • The purity of TIM1/HAVCR1 His Tag Protein, Human is greater than 95% as determined by SEC-HPLC.

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