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产品中心 药物靶点和Fc受体 药物靶点

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Glypican 1/GPC1 His Tag Protein, Human STAR

Glypican 1,GPC1

价格 ￥1,400.00 （ 供应商现货 ： 3-5个工作日）
货号 UA011160
规格
数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    Glypican 1, GPC1

  • Accession

    P35052-1

  • 表达序列

    Asp24-Ser530 with His Tag at the C-terminus

  • 表达宿主

    HEK293

  • 分子量

    58-130kDa (Reducing)

  • 纯度

    ＞95% by SDS-PAGE

  • 活性

    Immobilized FGF-basic(146aa) Protein, Human (Cat. No. UA040145) at 2.0μg/mL (100μL/well) can bind Glypican 1/GPC1 His Tag Protein, human (Cat. No. UA011160) with EC50 of 18.49-26.03ng/mL.

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, PH7.4, 5% trehalose

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    Adel I, Mahmoud HA, Khater AI, Hafez FS. Diagnostic value of glypican-1; a new marker differentiating pulmonary squamous cell carcinoma from adenocarcinoma: immunohistochemical study on Egyptian series. Clin Exp Med. 2025 Jan 11;25(1):35.

背景介绍

  • Glypican 1 has been shown to interact with SLIT2. This protein is involved in the misfolding of normal prion proteins in the cell membrane to the infectious prion form. Cell surface heparan sulfate proteoglycans consist of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the plasma membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.

  • 电泳

    • 1μg (R: reducing condition, N: non-reducing condition).

  • ELISA

    • Immobilized FGF-basic(146aa) Protein, Human (Cat. No. UA040145) at 2.0μg/mL (100μL/well) can bind Glypican 1/GPC1 His Tag Protein, human (Cat. No. UA011160) with EC50 of 18.49-26.03ng/mL.

    • Immobilized FGF-basic(154aa) Protein, Human (Cat. No. UA040007) at 2.0μg/mL (100μL/well) can bind Glypican 1/GPC1 His Tag Protein, Human (Cat. No. UA011160) with EC50 of 17.56-25.93ng/mL.

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