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物种
Mouse分子别名
CD354 antigen; CD354; TREM1; TREM-1; TREM-1Triggering receptor expressed on monocytes 1; triggering receptor expressed on myeloid cells 1; triggering-receptor TREM1Accession
Q9JKE2表达序列
Ala21-Ser202 with Human IgG1 Fc at C-Terminus表达宿主
HEK293分子量
55-72kDa (Reducing)
纯度
＞95% by SDS-PAGE &＞95% by SEC-HPLC内毒素含量
<0.1EU/μg标记
Unconjugated标签
Huamn IgG1 Fc性状
Lyophilized powder缓冲体系
PBS, PH7.4, 5% trehalose溶解方法
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
储存条件
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.文献引用
1.Bouchon A, Dietrich J, Colonna M. Cutting edge: inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes. J Immunol. 2000;164:4991–5.
The TREM-1 protein, a pivotal cell surface receptor, plays a crucial role in amplifying inflammatory responses within both the innate and adaptive immune systems. Activation of TREM-1 by ligands such as PGLYRP1, HMGB1, or HSP70 triggers multimerization of the receptor and subsequent complex formation with the signaling adaptors TYROBP (also known as DAP12).
电泳
1μg (R: reducing condition, N: non-reducing condition).
体积排阻色谱(SEC-HPLC)
The purity of TREM-1/CD354 Fc Chimera Protein, Mouse is greater than 95% as determined by SEC-HPLC.
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