TACI/CD267/TNFRSF13B Fc Chimera Protein, Human
CD267 antigen,CD267,CVID,CVID2,FLJ39942,MGC133214,TACI,TACIMGC39952,TNFRSF13B,TNFRSF14B,Transmembrane activator and CAML interactor,tumor necrosis factor receptor 13B,tumor necrosis factor receptor superfamily member 13B,tumor necrosis factor receptor superfamily,member 13B
分享产品介绍 评论(0)
物种
Human分子别名
CD267 antigen; CD267; CVID; CVID2; FLJ39942; MGC133214; TACI; TACIMGC39952; TNFRSF13B; TNFRSF14B; Transmembrane activator and CAML interactor; tumor necrosis factor receptor 13B; tumor necrosis factor receptor superfamily member 13B; tumor necrosis factor receptor superfamily, member 13BAccession
O14836-1表达序列
Ser2-Thr166 with Human IgG1 Fc at C-Terminus表达宿主
HEK293分子量
33-40kDa &43-55kDa (Reducing)纯度
> 95% by SDS-PAGE内毒素含量
<0.1EU/μg活性
Immobilized TACI/CD267/TNFRSF13B Fc Chimera Protein, Human (Cat. No. UA011118) at 1.0μg/mL (100μL/well) can bind Biotinylated BAFF Protein, human with EC50 of 1.47-2.12 ng/mL.标记
Unconjugated标签
Human IgG1 Fc性状
Lyophilized Powder缓冲体系
PBS, PH7.4, 5% trehalose溶解方法
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.储存条件
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.文献引用
1.Xia, X.-Z. et al. (2000) J. Exp. Med. 192:137.
2.von Bulow, G.U. et al. (1997) Science, 278:138.
3.Gross, J.A. et al. (2000) Nature 404:995.
4.Marsters, S.A. et al. (2000) Curr. Biol. 10:785.
5.Yan, M. et al. (2000) Nature Immunol. 1:37.
6.Wu, Y. et al. (2000) J. Biol. Chem. 275:35478.
TACI, transmembrane activator and CAML-interactor, is a member of the TNF receptor superfamily. TACI is a type III membrane protein with an extracellular N‑terminus in the absence of a cleaved signal sequence. Within the TNFRSF, it shares the highest homology with BCMA. TACI and BCMA have both been shown to bind APRIL and BAFF, members of the TNF ligand superfamily. TACI is expressed on the cell surface of B cells and activated, but not resting, T cells. Analogous to BCMA, data suggests that TACI may play an important role in B cell development, function and regulation. The expression of APRIL, BCMA and TACI were observed to be involved in extracellular signal-regulated kinase (ERK)1/2 activation in A549 cells.
电泳
1μg (R: reducing condition).
ELISA
Immobilized TACI/CD267/TNFRSF13B Fc Chimera Protein, Human (Cat. No. UA011118) at 1.0μg/mL (100μL/well) can bind Biotinylated BAFF Protein, human with EC50 of 1.47-2.12 ng/mL.
评论(0)