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物种
Human分子别名
TPBG,5T4, M6P1,5T4AG, WAIF1 ,5T4 oncofetal trophoblast glycoproteinAccession
Q13641表达序列
Ser32-Ser355 with His tag at the C-Terminus表达宿主
HEK293分子量
50-72kDa (Reducing)纯度
＞95% by SDS-PAGE & SEC-HPLC活性
Immobilized TPBG/5T4 His Tag Protein, Human (Cat. No. UA011109) at 2.0μg/mL (100μL/well) can bind TPBG Recombinant Monoclonal Antibody with EC50 of 1.26-2.59ng/mL.标记
Unconjugated标签
His Tag性状
Lyophilized Powder缓冲体系
PBS, PH7.4, 5% trehalose溶解方法
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.储存条件
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.文献引用
Li F, Wang Y, Cao J, Chen Q, Gao Y, Li R, Yuan L. Integrated analysis of genes shared between type 2 diabetes mellitus and osteoporosis. Front Pharmacol. 2024 Jun 20; 15:1388205.
Trophoblast glycoprotein (TPBG), also known as 5T4, is a therapeutic target for several anticancer agents in clinical development. This is primarily due to its high expression in tumors and low expression in normal adult tissues. The TPBG gene encodes a leucine-rich transmembrane glycoprotein that may play a role in cell adhesion. TPBG is expressed by all types of trophoblasts as early as the ninth week of development.
电泳
1μg (R: reducing condition, N: non-reducing condition).
体积排阻色谱(SEC-HPLC)
The purity of TPBG/5T4 His Tag Protein, Human is more than 95% determined by SEC-HPLC.
ELISA
Immobilized TPBG/5T4 His Tag Protein, Human (Cat. No. UA011109) at 2.0μg/mL (100μL/well) can bind TPBG Recombinant Monoclonal Antibody with EC50 of 1.26-2.59ng/mL.
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