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产品中心 药物靶点和Fc受体 药物靶点

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TREM-1/CD354 His Tag Protein, Mouse

Triggering receptor expressed on myeloid cells 1,TREM-1,CD354,Trem1

价格 ￥1,680.00 （ 供应商现货 ： 3-5个工作日）
货号 UA011108
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Mouse

  • 分子别名

    Triggering receptor expressed on myeloid cells 1; TREM-1; CD354; Trem1

  • Accession

    Q9JKE2

  • 表达序列

    Ala21-Ser202 with His Tag at C-Terminus

  • 表达宿主

    HEK293

  • 分子量

    33-50kDa (Reducing)

  • 纯度

    ＞95% by SDS-PAGE

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, PH7.4, 5% trehalose

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    Bouchon A, Dietrich J, Colonna M. Cutting edge: inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes. J Immunol. 2000;164:4991–5.

背景介绍

  • The TREM-1 protein, a pivotal cell surface receptor, plays a crucial role in amplifying inflammatory responses within both the innate and adaptive immune systems. Activation of TREM-1 by ligands such as PGLYRP1, HMGB1, or HSP70 triggers multimerization of the receptor and subsequent complex formation with the signaling adaptors TYROBP (also known as DAP12).

  • 电泳

    • 2ug (R: reducing condition, N: non-reducing condition).

  • 体积排阻色谱(SEC-HPLC)

    • The purity of TREM-1/CD354 His Tag Protein, Mouse is more than 90% determined by SEC-HPLC.

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