热搜词：
注册
登录
CN
  • CN
  • EN

产品中心 药物靶点和Fc受体 药物靶点

所有图片（1/3）

CD229/SLAMF3 His Tag Protein, Mouse

SLAMF3,Ly9,Ly-9

价格 ￥1,280.00 （ 供应商现货 ： 3-5个工作日）
货号 UA011098
规格
数量
收藏 分享
产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Mouse

  • 分子别名

    SLAMF3, Ly9, Ly-9

  • Accession

    Q4VBG4

  • 表达序列

    Lys48-Phe454 with His Tag at C-Terminus

  • 表达宿主

    HEK293

  • 分子量

    70-80kDa (Reducing)

  • 纯度

    ＞95% by SDS-PAGE & ＞90% by SEC-HPLC

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, PH7.4, 5% trehalose

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    Somuncular E, Su TY, Dumral Ö, Johansson AS, Luc S. Combination of CD49b and CD229 Reveals a Subset of Multipotent Progenitors With Short-Term Activity Within the Hematopoietic Stem Cell Compartment. Stem Cells Transl Med. 2023 Nov 3;12(11):720-726.

背景介绍

  • CD229, also known as Ly9 or SLAMF3, is a 120 kDa type I transmembrane glycoprotein belonging to the SLAM subgroup within the CD2 family. This protein is prominently expressed on T and B cells, thymocytes, and to a lesser extent on NK cells. The N-terminal Ig-like domain of CD229 facilitates homophilic binding between CD229 molecules.CD229/SLAMF3 serves as an autoligand receptor within the SLAM family, playing a crucial role in the regulation of immune cell activation and differentiation. It achieves this through homotypic or heterotypic interactions, which are essential for modulating immune responses.

  • 电泳

    • 2μg (R: reducing condition, N: non-reducing condition).

  • 体积排阻色谱(SEC-HPLC)

    • The purity of CD229/SLAMF3 His Tag Protein, Mouse is more than 90% determined by SEC-HPLC.

  • ELISA

    • Immobilized CD229/SLAMF3 His Tag Protein, Mouse (Cat. No. UA011098) at 2.0μg/mL (100μL/well) can bind Biotinylated CD229/SLAMF3 His Tag Protein, Mouse with EC50 of 7.33-10.18μg/mL.

评论(0)