BCMA/TNFRSF17 His Tag Protein, Cynomolgus
B-Cell Maturation Protein,B-Cell Maturation Factor,B Cell Maturation Antigen,CD269 Antigen,Tumor Necrosis Factor Receptor Superfamily Member 17,TNFRSF13A,CD269,BCM,TNF Receptor Superfamily Member 17,Tumor Necrosis Factor Receptor Superfamily,Member 17,B-Cell Maturation Antigen
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物种
Cynomolgus分子别名
B-Cell Maturation Protein，B-Cell Maturation Factor，B Cell Maturation Antigen，CD269 Antigen，Tumor Necrosis Factor Receptor Superfamily Member 17，TNFRSF13A，CD269，BCM，TNF Receptor Superfamily Member 17，Tumor Necrosis Factor Receptor Superfamily， Member 17，B-Cell Maturation AntigenAccession
XP_005591343.1浓度
＞95% by SDS-PAGE & SEC-HPLC表达序列
Met1-Ala53 with His Tag at the C-Terminus表达宿主
HEK293分子量
15-18kDa (Reducing)
内毒素含量
<0.1EU/μg活性
Immobilized BCMA/TNFRSF17 His Tag Protein, Cynomolgus (Cat. No. UA011094) at 2.0μg/mL (100μL/well) can bind Biotinylated Human APRIL/TNFSF13 Trimer Protein with EC50 of 0.64-1.04ng/mL.标记
Unconjugated标签
His Tag性状
Lyophilized Powder缓冲体系
PBS, PH7.4, 5% trehalose溶解方法
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
储存条件
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.文献引用
1. Gene ID: 608, updated on 18-Aug-2023.
B Cell Maturation Antigen (BCMA) also referred to as TNFRSF17 or CD269, is a transmembrane glycoprotein member of the tumor necrosis factor receptor (TNFR) superfamily. BCMA is a type III membrane protein containing one extracellular cysteine rich domain. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.
电泳
2μg (R: reducing condition, N: non-reducing condition).
体积排阻色谱(SEC-HPLC)
The purity of BCMA/TNFRSF17 His Tag Protein, Cynomolgus is greater than 95% as determined by SEC-HPLC.
ELISA
Immobilized BCMA/TNFRSF17 His Tag Protein, Cynomolgus (Cat. No. UA011094) at 2.0μg/mL (100μL/well) can bind Biotinylated Human APRIL/TNFSF13 Trimer Protein with EC50 of 0.64-1.04ng/mL.
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