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产品中心 药物靶点和Fc受体 药物靶点

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Ephrin-A1 Fc Chimera Protein, Human

EFNA1,LERK-1,TNFAIP4,EPLG1,B61,ECKLG,EFL1

价格 ￥1,000.00 （ 供应商现货 ： 3-5个工作日）
货号 UA011030
规格
数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    EFNA1, LERK-1, TNFAIP4, EPLG1, B61, ECKLG, EFL1

  • Accession

    P20827-1

  • 表达序列

    Asp19-Ser182, with hIgG Fc

  • 表达宿主

    HEK293

  • 分子量

    51-55 kDa (R)

  • 纯度

    ＞95% by SDS-PAGE & RP-HPLC

  • 活性

    Immobilized Biotinylated EphA2 His&Avi Tag Protein, Human (Cat. No. UA010833) at 2 μg/mL on Streptavidin precoated (0.5μg/well) plate, can bind Ephrin-A1 Fc Chimera Protein, Human (Cat. No. UA011030) with EC50 of 1.20-1.74 ng/ml.

  • 标记

    Unconjugated

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, PH7.4, 5% trehalose

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.

    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.

    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.

    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    1.Singh PK, Rybak JA, Schuck RJ, Barrera FN, Smith AW. Phosphatidylinositol (4,5)-bisphosphate drives the formation of EGFR and EphA2 complexes. bioRxiv [Preprint]. 2024 May 4:2024.05.03.592400. PMID: 38746348;

背景介绍

  • Ephrin-A1 (EFNA1) is also known as EPLG1, LERK1, TNFAIP4, Immediate early response protein B61, which belongs to the ephrin family. EFNA1 contains one ephrin RBD (ephrin receptor-binding) domain. EFNA1 is cell surface GPI-bound ligand for Eph receptors, and is a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development.

  • 电泳

    • 2μg (R: reducing condition, N: non-reducing condition).

  • 反相高效液相色谱(RP-HPLC)

    • The purity of Ephrin-A1 Fc Chimera Protein, Human is greater than 95% as determined by RP-HPLC.

  • ELISA

    • Immobilized Biotinylated EphA2 His&Avi Tag Protein, Human (Cat. No. UA010833) at 2 μg/mL on Streptavidin precoated (0.5μg/well) plate, can bind Ephrin-A1 Fc Chimera Protein, Human (Cat. No. UA011030) with EC50 of 1.20-1.74 ng/ml.

    • Immobilized EphA2 His Tag, Human (Cat. No. UA010580) at 2μg/mL (100μL/well) can bind Ephrin-A1 Fc Chimera Protein, Human (Cat. No. UA011030) with EC50 of 0.70-1.00 ng/ml.

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