分享产品介绍 评论(0)
物种
Cynomolgus分子别名
CD117, SCFR, c-Kit, KITAccession
XP_005555332.1表达序列
Gln26-Pro520, with C-terminal His表达宿主
HEK293分子量
75-95kDa (Reducing)
纯度
＞95% by SDS-PAGE &＞SEC-HPLC内毒素含量
<0.1EU/μg活性
Immobilized SCF Protein, Human (Cat. No. UA040138) at 2.0μg/mL (100μL/well) can bind CD117/c-Kit His Tag Protein, Cynomolgus (Cat. No. UA010933) with EC50 of 2.93-3.95 μg/mL.标记
Unconjugated标签
His Tag性状
Lyophilized Powder缓冲体系
PBS, 5% trehalose, PH7.4溶解方法
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
储存条件
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.文献引用
1. Wang H, Ni R, Wang A, Liu B. CD117 expression predicted FLT3 mutation in T-cell acute lymphoblastic leukemia. EJHaem. 2024 Feb 18;5(1):294-295.
2. Jiang YJ, Zhang CF, Wang HX, Zhao L, Zhang FF, Han XH. [Clinical Significance of Genetic and Molecular Changes in Primary Myeloid Sarcoma]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2024 Feb;32(1):27-32. Chinese.
Mast/stem cell growth factor receptor Kit (c-Kit), a member of the protein kinase superfamily, Tyr protein kinase family and CSF-1/PDGF receptor subfamily, is also known as piebald trait protein (PBT), p145 c-kit, tyrosine-protein kinase Kit and CD117,which contains five Ig-like C2-type (immunoglobulin-like) domains and one protein kinase domain. CD117 acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis.
电泳
体积排阻色谱(SEC-HPLC)
ELISA
Immobilized SCF Protein, Human (Cat. No. UA040138) at 2.0μg/mL (100μL/well) can bind CD117/c-Kit His Tag Protein, Cynomolgus (Cat. No. UA010933) with EC50 of 2.93-3.95 μg/mL.
评论(0)