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物种
Human分子别名
TACTILEAccession
P40200-2表达序列
Val22-Met503(C110S), with C-terminal His表达宿主
HEK293分子量
90-120kDa (Reducing)纯度
＞95% by SDS-PAGE内毒素含量
<0.1EU/μg标记
Unconjugated标签
His Tag性状
Lyophilized Powder缓冲体系
PBS, pH7.4.溶解方法
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.储存条件
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.文献引用
1.Eur J Immunol . 2020 Jun;50(6):891-902.Epub 2020 Feb 20.
Human CD96, also known as haptic (late expression of increased T cell activation), is a 160 kDa type I transmembrane glycoprotein of the Ig superfamily, with CD226, CD96 and TIGIT sharing the ligand CD155, which plays an important role in the regulation of NK cell function. Mature human CD96 contains an extracellular region of 498 aa, including three Igg-like domains. The two n-terminal domains are V-type structures, and the distal domains are C-type structures. Studies have shown that NK cells recognize the poliovirus receptor (PVR), a member of the connectin and connectin-like protein family that mediates cell-cell adhesion and cell migration in the presence of the CD96 receptor.
电泳
1μg (R: reducing condition, N: non-reducing condition).
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