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产品规格
物种
Human分子别名
CD171,L1CAMAccession
P32004表达序列
Ile20-Glu1120, with C-terminal His表达宿主
HEK293分子量
150-180kDa (Reducing)纯度
>95% by SDS-PAGE内毒素含量
<0.1EU/μg标记
Unconjugated标签
His Tag性状
Lyophilized Powder缓冲体系
PBS, pH7.4.溶解方法
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.储存条件
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.文献引用
1.Review Cell Adh Migr.2012 Jul-Aug;6(4):374-84. Epub 2012 Jul 1.
背景介绍
L1 cell adhesion molecule (L1CAM), also known as CD171, is a cell adhesion receptor in the immunoglobulin superfamily, which plays an important role in the development of the nervous system. L1CAM interacts with a variety of ligands. Including axon protein 1, CD9, neurocan, and integrins. The molecule is a type I transmembrane (TM) protein that contains an 1101 aa extracellular region (aa 20-1120) plus a 114 aa cytoplasmic domain (aa 1144-1257). Recent work has identified L1CAM (CD171) as a novel marker for human carcinoma progression, and a candidate for anti-cancer therapy.
电泳
1μg (R: reducing condition, N: non-reducing condition).







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