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产品中心 药物靶点和Fc受体 药物靶点

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CD10/Neprilysin/MME His Tag Protein, Mouse

MME,CALLA,CD10,DKFZp686O16152,MGC126681,MGC126707,NEP,SFE,Neprilysin

价格 ￥2,800.00 （ 供应商现货 ： 3-5个工作日）
货号 UA010894
规格
数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Mouse

  • 分子别名

    MME,CALLA,CD10,DKFZp686O16152,MGC126681,MGC126707,NEP,SFE,Neprilysin

  • Accession

    Q61391

  • 表达序列

    Tyr52-Trp750, with N-terminal His

  • 表达宿主

    HEK293

  • 分子量

    85-95kDa (Reducing)

  • 纯度

    ＞95% by SDS-PAGE

  • 内毒素含量

    <0.1EU/μg

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, pH7.4.

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    1.Review FASEB J . 1989 Feb;3(2):145-51.

背景介绍

  • Neprilysin (NEP, neutral endopeptidase 24.11, EC 3.4.24.11) is a zinc metallopeptidase, a 90-110-kDa type II transmembrane glycoprotein, which is usually expressed in a variety of tissues. Including the epithelial cells of the prostate, kidneys, intestines, endometrium, adrenal glands, and lungs. NEP has been identified as a common acute lymphoblastic leukemia antigen (CALLA) and is expressed on the surface of lymphocytes in certain disease states. Mutations in the CD10 gene can induce the familial forms of Alzheimer's disease, providing strong evidence for the protein's association with the Alzheimer's disease process.

  • 电泳

    • 1μg (R: reducing condition, N: non-reducing condition).

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