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产品中心 药物靶点和Fc受体 药物靶点

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CD300b/LMIR5/CD300LB Fc Chimera Protein, Human

CD300b Protein,Human,CLM-7 Protein,CLM7 Protein,CMRF35-A2 Protein,IREM-3 Protein,IREM3 Protein,TREM-5 Protein,TREM5 Protein

价格 ￥3,200.00 （ 供应商现货 ： 3-5个工作日）
货号 UA010844
规格
数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    CD300b Protein, Human; CLM-7 Protein, Human; CLM7 Protein, Human; CMRF35-A2 Protein, Human; IREM-3 Protein, Human; IREM3 Protein, Human; TREM-5 Protein, Human; TREM5 Protein, Human

  • Accession

    AAH28091

  • 表达序列

    Ile55-His187, with C-terminal hIgG1 Fc

  • 表达宿主

    HEK293

  • 分子量

    48-53kDa (Reducing)

  • 纯度

    ＞95% by SDS-PAGE

  • 内毒素含量

    <0.1EU/μg

  • 标记

    Unconjugated

  • 标签

    Human Fc Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, pH7.4.

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    1.Journal List Cell Death Differ v.21(11); 2014 Nov PMC4211373.

背景介绍

  • The CD300 receptor family members are a group of molecules that modulate a variety of immune cell processes. The CD300 receptor family consists of members with activating and inhibitory capabilities mainly expressed on the surface of immune cells. LMIR5, also known as CD300b, CD300LB, CLM-7, and IREM‑3, is a glycoprotein member of the immunoglobulin superfamily. Human LMIR5 consists of a 134 amino acid (aa) extracellular domain (ECD) with one Ig-like V-type domain, a 21 amino acid (aa) transmembrane segment, and a 29 aa cytoplasmic domain. Studies have shown that CD300b recognizes PS as a ligand and regulates phagocytosis of apoptotic cells through DAP12 signaling pathway.

  • 电泳

    • 1μg(R: reducing condition, N: non-reducing condition).

  • 体积排阻色谱(SEC-HPLC)

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