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ENPP3/CD203c His Tag Protein, Mouse

ENPP3,CD203c,NPP3,E-NPP3,PD-Ibeta,NPPase,PDNP3

价格 ￥2,800.00 （ 供应商现货 ： 3-5个工作日）
货号 UA010755
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Mouse

  • 分子别名

    ENPP3, CD203c, NPP3, E-NPP3, PD-Ibeta, NPPase, PDNP3

  • Accession

    Q6DYE8

  • 表达序列

    Arg46-Ile874, with N-terminal His Tag

  • 表达宿主

    HEK293

  • 分子量

    100-120kDa (Reducing)

  • 纯度

    ＞95% by SDS-PAGE

  • 内毒素含量

    <0.1EU/μg

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, pH7.4.

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    1.Yao, Wang, Han et al.[J] J Transl Med. (2023) 21 (1), 594.

背景介绍

  • NPP3 (CD203c, ENPP3) is a member of the human NPP family. NPP3 is expressed in multiple organs, including on epithelial and mucosal surfaces, and notably on basophils and mast cells. This protein is in fact a common marker for diagnosing allergen sensitivity with patient basophils by flow cytometry. Basophils and mast cells mediate the response to certain pathogens, as well as acute and chronic allergic reactions. Following activation, these cells release ATP, which further stimulates them in an autocrine manner. NPP3 upregulation serves to degrade ATP and suppress chronic allergic inflammation (but not the acute response).

  • 电泳

    • 1μg (R: reducing condition, N: non-reducing condition).

  • 体积排阻色谱(SEC-HPLC)

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