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产品中心 药物靶点和Fc受体 药物靶点

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CD55/DAF His Tag Protein, Mouse

CD55,DAF,CR,CROM,TC

价格 ￥3,020.00 （ 供应商现货 ： 3-5个工作日）
货号 UA010737
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Mouse

  • 分子别名

    CD55,DAF,CR,CROM,TC

  • Accession

    Q61475

  • 表达序列

    Asp35-T361, with C-10*His

  • 表达宿主

    HEK293

  • 分子量

    45-72kDa (Reducing)

  • 纯度

    ＞95% by SDS-PAGE

  • 内毒素含量

    <0.1EU/μg

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, pH7.4.

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    1.Journal List Immunology v.100(4); 2000 Aug PMC2327033.

背景介绍

  • CD55, also known as DAF or decay acceleration factor, is a 70-75 kDa member of the RCA protein family that is characterized by four to 30 SCRS (short consistent repeats) in its plasma exposure area. It prevents the assembly of the C3bBb complex (the C3-convertase of the alternative pathway) or accelerates the disassembly of preformed convertase, thus blocking the formation of the membrane attack complex. DAF seems to exert different functions beyond its immunological role such as promotion of tumorigenesis, decrease of complement mediated tumor cell lysis, autocrine loops for cell rescue and evasion of apoptosis, neoangiogenesis, invasiveness, cell motility.

  • 电泳

    • 2μg (R: reducing condition, N: non-reducing condition).

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