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物种
Human分子别名
CD2,SRBC,LFA-2,T11Accession
P06729表达序列
Lys25-Asp209, with C-8*His
表达宿主
HEK293分子量
33-40kDa (Reducing)
纯度
＞95% by SDS-PAGE内毒素含量
<0.1EU/μg标记
Unconjugated标签
His Tag性状
Lyophilized Powder缓冲体系
PBS, pH7.4.
溶解方法
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
储存条件
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
文献引用
1.Wilkins AL, et al. (2003) Structural biology of the cell adhesion protein CD2: from molecular recognition to protein folding and design. Curr Protein Pept Sci. 4(5): 367-73. 2.McNerney ME, et al. (2006) The CD2 family of natural killer cell receptors. Curr Top Microbiol Immunol. 298: 91-120
CD2 is an adhesion molecule present on the cell surface of T cells, natural killer (NK) cells, and B cells. T cell surface antigen CD2 is a type I glycoprotein belonging to the Ig superfamily and is expressed on T cells, NK cells, B cells and some antigen presenting cells. CD2-CD58 interactions play a critical role in the anti-tumor immune response, and restoration of this signaling is an important strategy for anti-tumor therapy.
电泳
1μg (R: reducing condition, N: non-reducing condition).
ELISA
Immobilized CD2/SRBC His Tag Protein, Human (Cat. No. UA010731 at 2 µg/mL (100 µL/well) can bind CD58/LFA-3 Fc Chimera Protein, Human with a linear range of 0.036–0.053μg/mL
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