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产品中心 药物靶点和Fc受体 药物靶点

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CLECSF6/DCIR/CLEC4A His Tag Protein, Human

CD367 Protein,Human,CLEC4A Protein,CLECSF6 Protein,DCIR Protein,DDB27 Protein,HDCGC13P Protein,LLIR Protein

价格 ￥4,230.00 （ 供应商现货 ： 3-5个工作日）
货号 UA010704
规格
数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    CD367 Protein, Human; CLEC4A Protein, Human; CLECSF6 Protein, Human; DCIR Protein, Human; DDB27 Protein, Human; HDCGC13P Protein, Human; LLIR Protein, Human

  • Accession

    Q9UMR7

  • 表达序列

    Gln70-Leu237, with N-terminal 8*His hhhhhhhhgggsQKYSQLLEKKTTKELVHTTLECVKKNMPVEETAWSCCPKNWKSFSSNCYFISTESASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEESAYFVGLSDPEGQRHWQWVDQTPYNESSTFWHPREPSDPNERCVVLNFRKSPKRWGWNDVNCLGPQRSVCEMMKIHL

  • 表达宿主

    HEK293

  • 分子量

    23-28kDa (Reducing)

  • 纯度

    ＞95% by SDS-PAGE

  • 内毒素含量

    <0.1EU/μg

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, pH7.4.

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    1.Gene ID: 50856, updated on 7-Sep-2023

背景介绍

  • DCIR, also known as Lectin-like Immunoreceptor (LLIR), is a type II membrane protein belonging to the C-type lectin domain family and is designated CLEC4A. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. DCIR expressed on antigen presenting cells and granulocytes and acts as an inhibitory receptor via an intracellular immunoreceptor tyrosine-based inhibitory motif (ITIM). It may also be involved via its ITIM motif in the inhibition of B-cell-receptor-mediated calcium mobilization and protein tyrosine phosphorylation.

  • 电泳

    • 1μg (R: reducing condition, N: non-reducing condition).

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