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产品中心 药物靶点和Fc受体 药物靶点

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CD68/SR-D1 His Tag Protein, Human

GP110,LAMP4,SCARD1

价格 ￥2,800.00 （ 供应商现货 ： 3-5个工作日）
货号 UA010665
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    GP110, LAMP4, SCARD1

  • Accession

    P34810

  • 表达序列

    Asn22-Ser319, with C-terminal 8*His

  • 表达宿主

    HEK293

  • 分子量

    55-95kDa

  • 纯度

    >95% by SDS-PAGE

  • 内毒素含量

    <0.1EU/μg

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, pH7.4

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    1． nature laboratory investigation pathobiology in focus article Published: 21 November 2016 CD68/macrosialin.

背景介绍

  • CD68 is a highly glycosylated glycoprotein, which has structural similarities with lysosome associated membrane protein (LAMP) and belongs to the LAMP family. Human CD68 contains 354 amino acids (aa), with a 21 aa signal sequence and a 298 aa extracellular domain (ECD), a 25 aa transmembrane domain, and a 10 aa cytoplasmic domain. CD68 is highly expressed by blood monocytes and tissue macrophages. CD68 plays a role in macrophage phagocytosis, intracellular lysosomal metabolism, extracellular cell-cell and cell-pathogen interactions. CD68 can be used alone or in combination with other cell markers of tumor-associated macrophages as a prognostic marker for cancer patient survival, showing good predictive value.

  • 电泳

    • 1μg (R: reducing conditions, N: non-reducing conditions).

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