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产品中心 药物靶点和Fc受体 药物靶点

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GARP/LRRC32 His Tag Protein, Mouse

GARP,Garpin,D11S833E

价格 ￥3,840.00 （ 供应商现货 ： 3-5个工作日）
货号 UA010645
规格
数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Mouse

  • 分子别名

    GARP, Garpin, D11S833E

  • Accession

    G3XA59

  • 表达序列

    Ile18-Asn628, with C-terminal 10*His

  • 表达宿主

    HEK293

  • 分子量

    75-80kDa

  • 纯度

    >95% by SDS-PAGE

  • 内毒素含量

    <0.1EU/μg

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, pH7.4

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.
背景介绍

  • LRRC32 encodes glycoprotein A Repeat Dominant (GARP), a cell surface receptor for TGFβ, an 80 kDa type I transmembrane glycoprotein. Mature mouse LRRC32 consists of a 608 amino acid (aa) extracellular domain (ECD) that contains 22 leucine-rich repeats, a 21 aa transmembrane segment, and a 14 aa cytoplasmic domain. LRRC32 is widely expressed during embryogenesis and on adult platelets. It is responsible for cell-surface docking of latent TGFβ before activation and release of the mature cytokine, and has an important role in maintaining peripheral tolerance and preventing inflammatory diseases.

  • 电泳

    • 1μg (R: reducing conditions, N: non-reducing conditions).

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