产品中心 药物靶点和Fc受体 药物靶点

所有图片(1/1)

CD34 His Tag Protein, Human

CD34 Molecule,CD34 Antigen,Hematopoietic Progenitor Cell Antigen CD34

价格 3,020.00 供应商现货 : 3-5个工作日
货号 UA010615
规格
数量
收藏 分享

产品介绍 评论(0)

产品规格
  • 物种

    Human
  • 分子别名

    CD34 Molecule, CD34 Antigen, Hematopoietic Progenitor Cell Antigen CD34
  • Accession

    P28906-1
  • 表达序列

    Ser32-Thr290, with C-terminal 8*His SLDNNGTATPELPTQGTFSNVSTNVSYQETTTPSTLGSTSLHPVSQHGNEATTNITETTVKFTSTSVITSVYGNTNSSVQSQTSVISTVFTTPANVSTPETTLKPSLSPGNVSDLSTTSTSLATSPTKPYTSSSPILSDIKAEIKCSGIREVKLTQGICLEQNKTSSCAEFKKDRGEGLARVLCGEEQADADAGAQVCSLLLAQSEVRPQCLLLVLANRTEISSKLQLMKKHQSDLKKLGILDFTEQDVASHQSYSQKTGGGSHHHHHHHH

  • 表达宿主

    HEK293
  • 分子量

    55-70kDa
  • 纯度

    >95% by SDS-PAGE
  • 内毒素含量

    <0.1EU/μg
  • 标记

    Unconjugated
  • 标签

    His Tag
  • 性状

    Lyophilized Powder
  • 缓冲体系

    PBS, pH7.4
  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.
  • 文献引用

    1.Civin C.I. et al. (1984) J. Immunol. 133:157. 2.Katz F. et al. (1985) Leuk. Res. 9:191. 3.Andrews R.G. et al. (1986) Blood 67:842.

背景介绍
  • Cluster of Differentiation 34 (CD34) is a member of a family of single-pass transmembrane sialomucin proteins, and may function as a cell-cell adhesion factor by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.CD34 protein is selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues. It has been widely used as a stem and progenitor cell marker, and clinical CD34+ stem cell transplantation (CD34+SCT) has been performed for tumor purging. CD34 monoclonal antibodies are widely used to identify and isolate hemopoietic progenitors and to classify acute and chronic leukemias.

  • 电泳

    • 1μg (R: reducing condition, N: non-reducing condition).

评论(0)