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物种
Human分子别名
STX4A, Syntaxin-4Accession
Q12846表达序列
Met1-Leu275, with N-terminal 8*His HHHHHHHHMRDRTHELRQGDDSSDEEDKERVALVVHPGTARLGSPDEEFFHKVRTIRQTIVKLGNKVQELEKQQVTILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKEEADENYNSVNTRMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDSGQSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGEMINRIEKNILSSADYVERGQEHVKTALENQKKARKKKVL
表达宿主
E.coli分子量
33kDa纯度
＞95% by SDS-PAGE内毒素含量
<0.1EU/μg标记
Unconjugated标签
His Tag性状
Lyophilized Powder缓冲体系
PBS, pH7.4溶解方法
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.储存条件
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.文献引用
1. Biochem Biophys Res Commun. 2013 Oct 11;440(1):163-7.
Syntaxin-4, a member of the Qa sensitive factor attachment protein receptor (SNARE) syntaxin family has been implicated in fusion events at the plasma membrane in a number of cells in the immune system. This protein enables sphingomyelin phosphodiesterase activator activity, and is active in glutamatergic synapse and postsynapse. Study demonstrates that syntaxin-4 plays a critical role in the secretion of IgE from plasma cells and sheds some light on the mechanisms by which these cells constitutively traffic vesicles to the surface for secretion. Together with STXB3 and VAMP2, it may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes and in docking of synaptic vesicles at presynaptic active zones (By similarity).
电泳JSON
1μg (R: reducing conditions, N: non-reducing conditions).
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