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产品中心 药物靶点和Fc受体 药物靶点

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MICB Fc Chimera Protein, Human

PERB11.2

价格 ￥2,960.00 （ 供应商现货 ： 3-5个工作日）
货号 UA010583
规格
数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Human

  • 分子别名

    PERB11.2

  • Accession

    Q29980-1

  • 表达序列

    Ala23-Asp309, with C-terminal Human IgG1 Fc

  • 表达宿主

    HEK293

  • 分子量

    72-85kDa

  • 纯度

    ＞95% by SDS-PAGE

  • 内毒素含量

    <0.1EU/μg

  • 标记

    Unconjugated

  • 标签

    Human Fc

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, pH7.4

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    1． Gene ID: 4277, updated on 21-Jun-2023.

背景介绍

  • MICB is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. Similar to classical MHC class I proteins, MICB contains three Ig-like domains ( alpha 1, alpha 2, and alpha 3) in the extracellular domain (ECD), a transmembrane segment, and a carboxy-terminal cytoplasmic tail.MICB is minimally expressed on normal cells, but are frequently expressed on epithelial tumors and can be induced by bacterial and viral infections.

  • 电泳

    • 1ug (R: reducing conditions, N: non-reducing conditions).

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