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产品中心 药物靶点和Fc受体 药物靶点

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EGFL6 Fc Chimera Protein, Mouse

Egfl6,Maeg,MGC141463 Protein

价格 ￥2,784.00 （ 供应商现货 ： 3-5个工作日）
货号 UA010525
规格
数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Mouse

  • 抗原名称

    EGFL6

  • 分子别名

    Egfl6, Maeg, MGC141463 Protein

  • Accession

    Q9JJZ5

  • 表达序列

    Thr287-Gly550, with C-terminal Human IgG1 Fc

  • 表达宿主

    HEK293

  • 分子量

    67-76kDa

  • 纯度

    ＞95% by SDS-PAGE

  • 内毒素含量

    <0.1EU/μg

  • 标记

    Unconjugated

  • 标签

    Human Fc

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, pH7.4

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    1. An, J., Du, Y., Fan, X. et al. EGFL6 promotes breast cancer by simultaneously enhancing cancer cell metastasis and stimulating tumor angiogenesis. Oncogene 38, 2123-2134 (2019). https://doi.org/10.1038/s41388-018-0565-9.

背景介绍

  • EGFL6, a member of the EGF-like superfamily, plays an important role during embryonic development and has been implicated in promotion of tumor angiogenesis without affecting wound healing. Importantly, expression of EGFL6 in cancer cells and tumor endothelial cells not only increased tumor angiogenesis but also promoted migration of cancer cells. Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of cell cycle, proliferation, and developmental processes. EGFL6 gene is expressed early during development, and its expression has been detected in lung and meningioma tumors.

  • 电泳

    • 1μg (R: reducing conditions, N: non-reducing conditions).

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