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物种
Human抗原名称
CEACAM-5/CD66e分子别名
CEA,Meconium antigen 100Accession
P06731表达序列
Lys35-Ala685, with C-terminal Human IgG1 Fc表达宿主
HEK293分子量
CEA, Meconium antigen 100纯度
＞95% by SDS-PAGE内毒素含量
<0.1EU/μg标记
FITC标签
Human Fc Tag性状
Lyophilized Powder缓冲体系
PBS, pH7.4储存条件
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.文献引用
1.Hammarstrom S. (1999). The carcinoembryonicantigen (CEA) family: structures, suggested functions and expression in normaland malignant tissues. Seminars in Cancer Biology. 9(2): 67-81.
The human CEA family has been fully characterized. It comprises 29 genes of which 18 are expressed; 7 belonging to the CEA subgroup and 11 to the pregnancy specific glycoprotein subgroup. CEA is an important tumor marker for colorectal and some other carcinomas. The CEA subgroup members are cell membrane associated and show a complex expression pattern in normal and cancerous tissues with notably CEA showing a selective epithelial expression. Several CEA subgroup members possess cell adhesion properties and the primordial member, biliary glycoprotein, seems to function in signal transduction or regulation of signal transduction possibly in association with other CEA sub-family members.
生物活性
Immobilized Anti-Human CEA(labetuzumab) Monoclonal Antibody at 2μg/ml (100 μl/well) can bind FITC-Labeled CEACAM-5 CD66e His Tag, Human with EC50 of 0.55μg/ml.
电泳
1μg (R: reducing conditions, N: non-reducing conditions).
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