热搜词：
注册
登录
CN
  • CN
  • EN

产品中心 药物靶点和Fc受体 药物靶点

所有图片（1/1）

SerpinC1/Antithrombin III His Tag Protein, Mouse

AT3,ATIII

价格 ￥4,320.00 （ 供应商现货 ： 3-5个工作日）
货号 UA010467
规格
数量
收藏 分享
产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Mouse

  • 抗原名称

    SerpinC1/Antithrombin III

  • 分子别名

    AT3, ATIII

  • Accession

    P32261

  • 表达序列

    His33-Asn465, with C-terminal 8*His

  • 表达宿主

    HEK293

  • 分子量

    55-72kDa (Reducing)

  • 纯度

    ＞95% by SDS-PAGE

  • 内毒素含量

    <0.1EU/μg

  • 标记

    Unconjugated

  • 标签

    His Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    PBS, pH7.4

  • 溶解方法

    Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
    · Please avoid repeated freeze-thaw cycles.

  • 文献引用

    1.Zeyuan Lu. Feng Wang. SerpinC1/Antithrombin IIIin kidney-related diseases. Clinical Science (2017) 131 823–831.

背景介绍

  • The gene SerpinC1 encodes a serine protease inhibitor named antithrombin III (ATIII).This protease demonstrates both anticoagulant and anti-inflammatory action. ATIII is the most important coagulation factor inhibitor, and even minor changes in ATIII can significantly alter the risk of thromboembolism. ATIII can also suppress inflammation via a coagulation-dependent or -independent effect. Moreover, apart from ATIII deficiency, ATIII and its gene SerpinC1 may also be related to many diseases (e.g. hypertension, kidney diseases). The present review summarizes how ATIII affects the progress of kidney disease and its mechanism.

  • 电泳

    • 1μg (R: reducing condition, N: non-reducing condition).

评论(0)