分享产品介绍 评论(0)
物种
Mouse抗原名称
MOG分子别名
BTN6,BTNL11,MOGIG2,NRCLP7,Myelin oligodendrocyte glycoproteinAccession
Q61885表达序列
Gly29-Gly153,with C-terminal 8*His
表达宿主
HEK293分子量
19-22kDa (Reducing)
纯度
>95% by SDS-PAGE
内毒素含量
<0.1EU/μg标记
Unconjugated标签
His Tag性状
Lyophilized Powder缓冲体系
PBS, pH7.4
溶解方法
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
储存条件
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
文献引用
1. Reindl, M. et al. (2013) Nat. Rev.Neurol. 9:455.
Myelin oligodendrocyte glycoprotein (MOG) is a transmembrane protein belonging to immunoglobulin superfamily. Mouse MOG is synthesized with a 28 amino acid (aa) signal sequence, a 128 aa extracellular domain (ECD) containing an Ig-like domain, a 21 aa transmembrane domain, and a 69 aa cytosolic fragment featuring a hydrophobic domain that associates with the cytoplasmic face of the plasma membrane. MOG is expressed exclusively by oligodendrocytes in the central nervous system (CNS) and is localized to the outer layer of the myelin sheath as well as in the oligodendrocyte plasma membrane. This makes MOG a potential target of cellular and humoral immune responses in inflammatory demyelinating diseases.
电泳
- 1μg (R: reducing condition, N: non-reducing condition).
ELISA
Immobilized MOG His Tag Protein, Mouse (Cat. No. UA010433) at 2.0μg/mL (100μL/well) can bind Myelin Oligodendrocyte Glycoprotein (MOG) Recombinant Rabbit mAb (S-1384-61) (Cat. No. S0B0812) with EC50 of 0.92-1.16ng/mL.
评论(0)