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IL-3 Rα/CD123 His Tag Protein, Human
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IL-3 Rα/CD123 His Tag Protein, Mouse
规格：100μg
价格：￥2,450.00
IL-3 Protein, Human
规格：10μg
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产品介绍 评论(0)
产品规格
物种
MouseAccession
P26952-1表达序列
Ser17-Lys331, with C-terminal Human IgG1 Fc表达宿主
HEK293分子量
80-91kDa (Reducing)纯度
>95% by SDS-PAGE
内毒素含量
<0.1EU/μg标记
Unconjugated标签
Human Fc Tag性状
Lyophilized Powder缓冲体系
PBS, pH7.4溶解方法
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.储存条件
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
背景介绍
Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 45-62kDa glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells.
生物活性
- IL-3 Rα/CD123 Fc Chimera, Mouse (Cat. No. UA010122) captured on Protein A Biosenor, can bind IL-3, Mouse (Cat. No. UA040064) with an affinity constant of 0.17 μM as determined in SPR assay.
电泳
- 1μg (R: reducing conditions, N: non-reducing conditions).
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