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产品中心 药物靶点和Fc受体 药物靶点

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Complement C5a Protein, Mouse

Complement Component C5a

价格 ￥3,680.00 （ 供应商现货 ： 3-5个工作日）
货号 UA010080
规格
数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 物种

    Mouse

  • 分子别名

    Complement Component C5a

  • Accession

    P06684

  • 表达序列

    Met+Asn679-Arg755

  • 表达宿主

    E.coli

  • 分子量

    10kDa (Reducing)

  • 纯度

    ＞95% by SDS-PAGE & RP-HPLC

  • 内毒素含量

    <1EU/μg

  • 标记

    Unconjugated

  • 标签

    No Tag

  • 性状

    Lyophilized Powder

  • 缓冲体系

    20mM Tris, 300mM NaCl, pH8.0

  • 溶解方法

    Reconstitute at 0.5-1mg/ml according to the size in ultrapure water after rapid centrifugation.

  • 储存条件

    · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.

    · 3 months, -20 to -80℃ under sterile conditions after reconstitution.

    · 1 week, 2 to 8℃ under sterile conditions after reconstitution.

    · Please avoid repeated freeze-thaw cycles.

背景介绍

  • Complement Component C5a (C5a) is also known as C5, and is a protein fragment released from complement component C5. C5a is an extremely potent proinflammatory mediator, as well as a potent chemotactic factor for neutrophils and other leukocytes. It causes histamine release, increases in vascular permeability, induces several cytokines production from leukocytes, enhances neutrophil-endothelial cell adhesion, and augments the humoral and cell-mediated immune response. C5a is also chemotactic for dendritic cells (DCs), germinal center B cells, and T cells. Thus, anaphalatoxins participate in the recruitment of various leukocytes into sites of inflammation during infection and tissue injury.

  • 电泳

    • 2μg（R: reducing conditions, N: non-reducing conditions)

  • 反相高效液相色谱(RP-HPLC)

  • ELISA

    • Immobilized Complement C5a Protein, Mouse (Cat. No. UA010080) at 2.0μg/mL (100μL/well) can bind Mouse C5a Recombinant mAb (SDT-2892-38) (Cat. No. S0B3690) with EC50 of 0.35-0.40 ng/mL.

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