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物种
Human分子别名
neuron-glial antigen 2,NG2,high molecular weight-melanoma associated antigen,HMW-MAA)Accession
Q6UVK1表达序列
Ser1583-Ser2224, with C-terminal 10*His表达宿主
HEK293分子量
90-110 kDa(Reducing)
纯度
＞95% by SDS-PAGE
内毒素含量
<0.1EU/μg标记
Unconjugated性状
Lyophilized Powder缓冲体系
PBS, pH7.4溶解方法
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
储存条件
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
CSPG4 (also known as neuron-glial antigen 2, NG2, and high molecular weight-melanoma associated antigen, HMW-MAA) is key component of cell migration and proliferation. CSPG4 has been associated with disease severity in other tumors. Expression of CSPG4 could be a useful prognostic biomarker in chordoma. As CSPG4 is expressed on the cell-surface, it is also an attractive candidate for targeting by a CSPG4-specific antibody.
电泳
- 2 μg（R: reducing conditions, N: non-reducing conditions).
ELISA
Immobilized NG2/CSPG4 His Tag, Human (Cat. No. UA010060) at 2.0μg/mL (100μL/well) can bind NG2 Chondroitin Sulfate Proteoglycan Recombinant Rabbit mAb (S-1233-25) (Cat. No. S0B0866) with EC50 of 0.92-1.20ng/mL.
引用文献(1)
- Chondroitin sulfate proteoglycan 4 (CSPG4) overexpression as an oncogenic driver and prognostic marker for unfavorable outcomes in hepatocellular carcinoma
Ren C, Yan F, Xiang H, Hong T, Mierxiati A, Zhang L, Wang M, Wang C.
World J Surg Oncol. 2025 Dec 02 .
影响因子： 2.5
货号：UA010060产品名称：NG2/CSPG4 His Tag Protein, Human
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