热搜词：
注册
登录
CN
  • CN
  • EN

产品中心 药物靶点和Fc受体 药物靶点

所有图片（1/2）

LILRB3/CD85a/LIT5 Fc Chimera Protein, Human

价格 ￥3,000.00 （ 供应商现货 ： 3-5个工作日）
货号 UA010021
规格
数量
收藏 分享

关联产品推荐

  • LILRB1/CD85j/ILT2 Fc Chimera Protein, Human

    规格：100μg

    价格：￥3,000.00

  • LILRB2/CD85d/ILT4 Fc Chimera Protein, Human

    规格：100μg

    价格：￥3,000.00

  • LILRA3/CD85e Fc Chimera Protein, Human

    规格：100μg

    价格：￥3,600.00

  • LILRA6/CD85b/ILT8 Fc Chimera Protein, Human

    规格：100μg

    价格：￥4,000.00

  • LILRA5/CD85f/ILT11 Fc Chimera Protein, Human

    规格：100μg

    价格：￥4,000.00

    • 产品介绍

    产品介绍 评论(0)

    产品规格

    • 物种

      Human

    • Accession

      O75022

    • 表达序列

      Gly24-Glu443, with C-terminal Human IgG Fc

    • 表达宿主

      HEK293

    • 分子量

      85-95kDa(Reducing)

    • 纯度

      ＞95%, by SDS-PAGE under reducing conditions

    • 内毒素含量

      <0.1EU/μg

    • 标记

      Unconjugated

    • 标签

      Human Fc Tag

    • 性状

      Lyophilized Powder

    • 缓冲体系

      PBS, pH7.4

    • 溶解方法

      Reconstitute at less than 1 mg/mL according to the size in ultrapure water after rapid centrifugation .

    • 储存条件

      · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.

      · 3 months, -20 to -80℃ under sterile conditions after reconstitution.

      · 1 week, 2 to 8℃ under sterile conditions after reconstitution.

      · Please avoid repeated freeze-thaw cycles.

    背景介绍

    • LILRB3 is a member of LILRB family that is restrictively expressed on myeloid cells, including monocytes, neutrophils, eosinophils, and basophils (as well as on in vitro differentiated mast cells and osteoclasts). LILRB3 contains four cytoplasmic ITIM motifs hat may contribute to negative regulation of immune response. Ligation of LILRB3 in human myeloid cells led to inhibition of immune activation. LILRB3 may be an inhibitor of allergic inflammation and autoimmunity. However, the ligand for LILRB3 has not been identified, and the downstream signaling of LILRB3 is unclear. It is noteworthy that LILRBs, including LILRB3, are primate specific.

      LILRB3 is also expressed on some myeloid leukemia, B lymphoid leukemia, and myeloma cells. It is reportedly co-expressed with stem cell marker CD34 and with myeloma marker CD138.

    • 电泳

      • LILRB3/CD85a/LIT5 Fc Chimera, Human，1μg on SDS-PAGE under Non-reducing and reducing condition. The purity is greater than 95%.

    • ELISA

      • Immobilized LILRB3/CD85a/LIT5 Fc Chimera Protein, Human(Cat. No. UA010021) at 2μg/ml (100μl/well) can bind ANGPTL7 Fc Chimera Protein, Human with EC50 of 46.68-54.04ng/ml.

    评论(0)