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Nectin-1/PVRL1/CD111 Fc Chimera Protein, Human

Poliovirus Receptor-Related Protein 1,Herpes Virus Entry Mediator C,Herpesvirus Entry Mediator C,HveC,Herpesvirus Ig-Like Receptor,HIgR,Nectin-1,CD111,PVRL1,HVEC,PRR1

货号： UA010016

Datasheet COA
  • 价格： ￥1,800
  • 规格：
  • 数量：
斯达特大包装询价 大包装询价

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  • Nectin-1/PVRL1/CD111 His Tag Protein, Human

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    • 产品介绍 评论(0)

    产品规格

    • 物种

      Human

    • 分子别名

      Poliovirus Receptor-Related Protein 1,Herpes Virus Entry Mediator C,Herpesvirus Entry Mediator C,HveC,Herpesvirus Ig-Like Receptor,HIgR,Nectin-1,CD111,PVRL1,HVEC,PRR1

    • Accession

      Q15223-1

    • 表达序列

      Gln31-Thr334, with C-terminal Human IgG1 Fc

    • 表达宿主

      HEK293

    • 分子量

      80-90kDa(reducing)

    • 纯度

      ＞95%, by SDS-PAGE under reducing conditions

    • 内毒素含量

      <0.1EU/μg

    • 标记

      Unconjugated

    • 标签

      Human Fc Tag

    • 性状

      Lyophilized powder

    • 缓冲体系

      PBS, pH7.4

    • 溶解方法

      Reconstitute at less than 1 mg/mL according to the size in ultrapure water after rapid centrifugation .

    • 储存条件

      · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
      · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
      · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
      · Please avoid repeated freeze-thaw cycles.

    • 稀释度

    背景介绍

    • Nectin-1, also referred to as ED4, is a poliovirus receptor- related 1 protein is a part of the Nectin family. Nectin-1 endorses cell-cell contacts by forming homophilic or heterophilic trans-dimers. Heterophilic interactions among PVRL1/nectin-1 & PVRL4/nectin-4 and among PVRL1/nectin-1 & PVRL3/nectin-3 have been found. Nectin-1 acts as an entry receptor for herpes simplex virus & pseudorabies virus as well. Likewise, Neurite outgrowth-promoting activity has been shown by Nectin-1.

    • 生物活性

      • Anti-His antibody Immobilized on CM5 Chip captured Nectin-4 His Tag, Human (Cat. No. UA010020), can bind Nectin-1 Fc Chimera, Human (Cat. No. UA010016) with an affinity constant of 0.521μM as determined in SPR assay.
      • Immobilized Nectin-4 His Tag, Human (Cat. No. UA010020) at 5μg/mL (100μL/well) can bind Nectin-1 Fc Chimera, Human (Cat. No. UA010016) with EC50 of 0.184μg/mL.

      • Protein A Chip captured Nectin-1/PVRL1/CD111 Fc Chimera, Human (Cat. No. UA010016), can bind Nectin-3/CD113 His Tag, Human (Cat. No. UA010487) with an affinity constant of 20.01μM as determined in SPR assay.

    • 电泳

      • Nectin-1/PVRL1/CD111 Fc Chimera, Human ，1μg on SDS-PAGE under reducing and Non-reducing condition. The purity is greater than 95%.

    • ELISA

      • Immobilized Nectin-3/CD113 His Tag, Human (Cat. No. UA010487) at 2.0μg/mL (100μL/well) can bind Nectin-1/PVRL1/CD111 Fc Chimera, Human (Cat. No. UA010016) with EC50 of 5.43-10.29ng/ml.

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