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产品中心 药物靶点和Fc受体 药物靶点

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Biotinylated SIRP-α Fc Chimera Protein, Human

Biotinylated SIRP-α Fc Chimera protein,BIT,BITbrain-immunoglobulin-like molecule with tyrosine-based activation motifs,Brain Ig-like molecule with tyrosine-based activation motifs,CD172 antigen-like family member A,CD172a antigen,CD172a,Inhibitory receptor SHPS-1,Macrophage fusion receptor,MFR,MFRtyrosine phosphatase SHP substrate 1,MyD-1 antigen,MYD1,MYD-1,P84,protein tyrosine phosphatase,non-receptor type substrate 1,PTPNS1,SHP substrate 1,SHPS1,SHPS-1,SHPS1CD172A,signal-regulatory protein alpha,Signal-regulatory protein alpha-1,Signal-regulatory protein alpha-2,Signal-regulatory protein alpha-3,SIRP alpha,SIRPA,SIRPalpha,Sirp-alpha-1,SIRPalpha2,Sirp-alpha-2,Sirp-alpha-

价格 ￥2,800.00 （ 供应商现货 ： 3-5个工作日）
货号 UA010008
规格
数量
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    • 产品介绍

    产品介绍 评论(0)

    产品规格

    • 物种

      Human

    • 分子别名

      Biotinylated SIRP-α Fc Chimera protein ;BIT, BITbrain-immunoglobulin-like molecule with tyrosine-based activation motifs, Brain Ig-like molecule with tyrosine-based activation motifs, CD172 antigen-like family member A, CD172a antigen, CD172a, Inhibitory receptor SHPS-1, Macrophage fusion receptor, MFR, MFRtyrosine phosphatase SHP substrate 1, MyD-1 antigen, MYD1, MYD-1, P84, protein tyrosine phosphatase, non-receptor type substrate 1, PTPNS1, SHP substrate 1, SHPS1, SHPS-1, SHPS1CD172A, signal-regulatory protein alpha, Signal-regulatory protein alpha-1, Signal-regulatory protein alpha-2, Signal-regulatory protein alpha-3, SIRP alpha, SIRPA, SIRPalpha, Sirp-alpha-1, SIRPalpha2, Sirp-alpha-2, Sirp-alpha-

    • Accession

      P78324

    • 表达序列

      Glu31-Arg370, with C-terminal Human IgG1 Fc&Avi tag

    • 表达宿主

      HEK293

    • 分子量

      150 kDa(Non-reducing)

    • 纯度

      ＞90%, by SDS-PAGE under Non-reducing conditions

    • 内毒素含量

      <0.1EU/μg

    • 标记

      Biotin

    • 标签

      Human Fc Tag

    • 性状

      Lyophilized Powder

    • 缓冲体系

      PBS pH7.2，5% trehalose

    • 溶解方法

      Reconstitute at less than 1 mg/mL according to the size in deionized water after rapid centrifugation.

    • 储存条件

      · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
      · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
      · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
      · Please avoid repeated freeze-thaw cycles.
    背景介绍

    • 信号调节蛋白α(Signal Regulatory Proteinα, SIRPα)也称为SHPS-1，是一种跨膜蛋白，SIRP-α在髓系细胞膜上高表达，如巨噬细胞、粒细胞、单核细胞和髓样树突状细胞。它可以调节细胞迁移和吞噬活动，以及免疫稳态和神经网络的形成。

    • 生物活性

      • Immobilized Human CD47 Fc Chimera(Cat. No. UA010006) at 1 μg/mL (100 μL/well) can bind Biotinylated SIRP-α Fc Chimera, Human (Cat. No. UA010008) with EC50 of 0.057 μg/mL.

    • 电泳

      • 1 μg (R: reducing conditions, N: non-reducing conditions).

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