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产品中心 药物靶点和Fc受体 药物靶点

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Biotinylated CD47 Fc Chimera Protein, Human

Biotinylated CD47 Fc Chimera protein,antigen identified by monoclonal 1D8,Antigenic surface determinant protein OA3,CD47 antigen (Rh-related antigen,integrin-associated signal transducer),CD47 antigen,CD47 glycoprotein,CD47 molecule,CD47,IAP,IAPintegrin associated protein,Integrin-associated protein,leukocyte surface antigen CD47,MER6,MER6integrin-associated signal transducer,OA3,Protein MER6,Rh-related antigen

价格 ￥2,700.00 （ 供应商现货 ： 3-5个工作日）
货号 UA010007
规格
数量
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  • CD47 His Tag Protein, Human

    规格：25μg

    价格：￥1,300.00

    • 产品介绍

    产品介绍 评论(0)

    产品规格

    • 物种

      Human

    • 分子别名

      Biotinylated CD47 Fc Chimera protein;antigen identified by monoclonal 1D8, Antigenic surface determinant protein OA3, CD47 antigen (Rh-related antigen, integrin-associated signal transducer), CD47 antigen, CD47 glycoprotein, CD47 molecule, CD47, IAP, IAPintegrin associated protein, Integrin-associated protein, leukocyte surface antigen CD47, MER6, MER6integrin-associated signal transducer, OA3, Protein MER6, Rh-related antigen

    • Accession

      Q08722

    • 表达序列

      Gln19-Pro139, with C-terminal Human IgG1 Fc&Avi tag

    • 表达宿主

      HEK293

    • 分子量

      110 kDa(Non-reducing)

    • 纯度

      ＞95%, by SDS-PAGE under reducing conditions

    • 内毒素含量

      <0.2EU/μg

    • 标记

      Biotin

    • 标签

      Human Fc Tag

    • 性状

      Lyophilized Powder

    • 缓冲体系

      PBS pH7.2, 5% trehalose

    • 溶解方法

      Reconstitute at less than 1 mg/mL according to the size in ultrapure water after rapid centrifugation .

    • 储存条件

      · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
      · 3 months, -20 to -80℃ under sterile conditions after reconstitution.
      · 1 week, 2 to 8℃ under sterile conditions after reconstitution.
      · Please avoid repeated freeze-thaw cycles.
    背景介绍

    • CD47 (Cluster of Differentiation 47), also known as integrin associated protein (IAP), is a transmembrane protein that in humans is encoded by the CD47 gene. It belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory protein alpha (SIRPα). CD47 is involved in a range of cellular processes, including apoptosis, proliferation, adhesion, and migration. Furthermore, it plays a key role in immune and angiogenic responses. Also CD47 is ubiquitously expressed in human cells and has found to be overexpressed in many different tumor cells.

    • 生物活性

      • Immobilized Human SIRP-α Fc Chimera, Human (Cat. No. UA010005) at 1 μg/mL (100μL/well) can bind Biotinylated Human CD47 Fc Chimera (Cat. No. UA010007) with EC50 of 0.067 μg/mL.

    • 电泳

      • Biotinylated Recombinant Human CD47, Fc Chimera 0.5μg on SDS-PAGE under Non-reducing condition. The purity is greater than 95%.

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