Dog IgG OneStep ELISA Kit

Dog immunoglobulin G (IgG) is the predominant and most versatile antibody class in canine serum, serving as the cornerstone of the humoral adaptive immune response in dogs (Canis lupus familiaris). It provides long-term protection by neutralizing pathogens, enhancing phagocytosis through opsonization, and activating the complement system. Structurally typical of mammalian IgG, it comprises several functionally distinct subclasses—commonly identified as IgG-A, IgG-B, IgG-C, and IgG-D—each specialized for different immune challenges, such as bacterial infections, parasitic responses, or allergies. A key biochemical feature is the strong affinity of certain subclasses (particularly those analogous to human IgG1) for Protein A and Protein G, which facilitates its use in research and diagnostics. Given the dog's dual role as a cherished companion animal and a premier translational model for human diseases (including cancer, autoimmune disorders, and immunology), dog IgG holds immense importance. It is indispensable in veterinary medicine for disease diagnosis and vaccine assessment, and in biomedical research as a vital reagent for immunoassays, therapeutic antibody development, and comparative immunological studies.