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产品中心 ELISA试剂盒 OneStep ELISA 试剂盒

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Human & Monkey CXCL10/IP-10(serum/plasma) OneStep ELISA Kit

价格 ￥3,000.00 （ 1-2周）
货号 S0C3103
规格
数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 抗原名称

    CXCL10

  • 免疫原

    Recombinant Protein

  • 抗体类型

    Recombinant mAb

  • 反应种属 ?

    Hu, Mk

  • 纯化方式

    Protein A

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8'C as supplied.

试剂盒参数

    • Precision

      Intra-assay: 4.7%；
      Inter-assay: 8.1%

    • Sample type

      Serum; Plasma

    • Assay type

      Sandwich (quantitative)

    • Sensitivity

      1.222 pg/mL

    • Range

      2.34 pg/mL – 150 pg/mL

    • Recovery

      Serum: 111%
      Plasma: 100%

    • Assay time

      60 minutes

    • Species reactivity

      Hu; Mk
背景介绍

  • CXCL10 is a small signaling protein classified as a chemokine. It is primarily produced by cells like macrophages and fibroblasts in response to interferon-gamma. Its main function is to act as a chemoattractant, guiding immune cells to sites of inflammation or infection. Specifically, CXCL10 binds to a receptor called CXCR3, which is found on the surface of activated T cells and natural killer (NK) cells. This interaction is crucial for mounting an effective immune response against viruses and intracellular pathogens. Consequently, CXCL10 plays a significant role in autoimmune diseases, chronic inflammation, and anti-tumor immunity. Its expression is often used as a biomarker for Th1-type immune responses. In summary, CXCL10 is a key mediator that recruits specific immune cells to coordinate the body's defense mechanisms.

  • ELISA

    • Standard curve
      Example of Mouse Human CXCL10 curve in Assay Diluent #11.

    • Linearity
      The concentrations of Human CXCL10 were measured and interpolated from the target standard curves and corrected for sample dilution.
      Sample is undiluted samples are as follows: human plasma was 2fold dilution (50%). The interpolated dilution factor corrected values are plotted. The mean target concentration was determined to be 140.24 pg/mL in stimulated human plasma.

    • Linearity
      The concentrations of Human CXCL10 were measured and interpolated from the target standard curves and corrected for sample dilution.
      Sample is undiluted samples are as follows: human serum was 2fold dilution (50%). The interpolated dilution factor corrected values are plotted. The mean target concentration was determined to be 152.57 pg/mL in stimulated human serum.

    • Linearity
      The concentrations of Human CXCL10 were measured and interpolated from the target standard curves and corrected for sample dilution.
      Sample is undiluted samples are as follows: monkey serum was 16fold dilution (6.25%). The interpolated dilution factor corrected values are plotted. The mean target concentration was determined to be 310.52 pg/mL in stimulated monkey serum.

    • Specificity
      Test the specificity of different serum.

    • Leading Competitor comparison

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