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宿主来源
Armenian hamster抗原名称
CD36分子别名
Platelet glycoprotein 4; Glycoprotein IIIb (GPIIIB); PAS IV; PAS-4; Platelet glycoprotein IV (GPIV); Cd36细胞定位
Cell membraneAccession
Q08857克隆号
HM36抗体类型
Recombinant mAb抗体同种型
IgG反应种属 ?
Ms阳性样本
Mouse peritoneal exudates cells纯化方式
Protein G浓度
0.5 mg/ml标记
Alexa Fluor® 700性状
Liquid缓冲体系
PBS, 1% BSA, 0.3% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 1μg per million cells in 100μl volume Ms
CD36 is a heavily glycosylated 80kD integral membrane protein widely expressed on platelets, immune cells, adipocytes, myocytes, enterocytes, enteroendocrine cells, and other cell types. It is a member of the class B scavenger receptor family and functions as a pattern recognition receptor. CD36 has a diverse range of ligands and physiological functions, including the uptake of modified lipids and apoptotic cells, long-chain fatty acid transport, adhesion, and angiogenesis. It plays a role in various pathological conditions such as atherosclerosis, diabetes, and cardiomyopathy. In the gut, CD36 promotes absorption of long-chain fatty acids and participates in carotenoid uptake for vitamin A metabolism. It also acts as a receptor for thrombospondin-1 and several other proteins containing thrombospondin type I repeats, functioning as an endogenous negative regulator of angiogenesis on microvascular endothelial cells.
流式分析
Flow cytometric analysis of mouse CD36 expression on mouse peritoneal exudates cells. Mouse peritoneal exudates cells were stained with Pacific Blue™ Rat Anti-Mouse F4/80 Antibody and either Alexa Fluor® 700 Armenian Hamster IgG Isotype Control (left panel) or SDT Alexa Fluor® 700 Armenian Hamster Anti-Mouse CD36 Antibody (right panel) at 2 μl/test. Flow cytometry and data analysis were performed using Agilent NovoCyte Quanteon and FlowJo™ software.
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