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宿主来源
Mouse抗原名称
CD44H分子别名
CD44s, CD44A, METAA, RHAMM, CD44, Pgp-1, H-CAM, CD44st, CD44std细胞定位
Secreted, Cell membraneAccession
P26051克隆号
OX-49抗体类型
Mouse mAb抗体同种型
IgG2a,k反应种属 ?
Rt阳性样本
SD Rat splenocytes纯化方式
Protein A浓度
0.5 mg/ml标记
Alexa Fluor® 488性状
Liquid缓冲体系
PBS, 1% BSA, 0.3% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 1μg per million cells in 100μl volume Rt
CD44H, also termed CD44s or the “standard/hematopoietic” isoform, is the smallest CD44 splice variant (≈37 kDa core, 80–95 kDa fully glycosylated) that lacks all variably spliced exons and functions as the cell’s dominant hyaluronan receptor, orchestrating hematopoietic progenitor trafficking, T-cell activation, angiogenesis, and tumor metastasis by coupling extracellular matrix adhesion to cytoskeletal signaling through its cytoplasmic tail-ERM-actin linkage and by serving as a membrane scaffold for metalloproteinases and growth-factor presentation.
流式分析
Flow cytometric analysis of Rat CD44H expression on SD Rat splenocytes. SD Rat splenocytes were stained with Allophycocyanin Mouse Anti-Rat CD3 Antibody and either Alexa Fluor® 488 Mouse IgG2a, κ Isotype Control (left panel) or SDT Alexa Fluor® 488 Mouse Anti-Rat CD44H Antibody (right panel) at 2μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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