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Biotin Mouse Anti-Human CD66a/c/e Antibody (S-3923)

CEACAM1,BGP-1,BGP,BGP1,CEACAM6,NCA,CEACAM5,CEA

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货号 S0B8741
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产品规格
  • 宿主来源

    Mouse
  • 抗原名称

    CD66a/c/e
  • 分子别名

    CEACAM1; BGP-1; BGP; BGP1; CEACAM6; NCA; CEACAM5; CEA
  • 细胞定位

    Cell membrane
  • Accession

    P13688, P40199, P06731
  • 克隆号

    S-3923
  • 抗体类型

    Mouse mAb
  • 抗体同种型

    IgG2b,k
  • 反应种属 ?

    Hu
  • 阳性样本

    human peripheral blood leukocytes
  • 纯化方式

    Protein A
  • 浓度

    0.2 mg/ml
  • 标记

    Biotin
  • 性状

    Liquid
  • 缓冲体系

    PBS pH7.4, 0.03% Proclin 300

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

  • 应用

    FCM

  • 稀释度

    应用 稀释度 推荐种属
    FCM 5μl per million cells in 100μl volume Hu
背景介绍
  • CD66a/c/e are closely related glycoproteins of the carcinoembryonic-antigen family that share an N-terminal IgV-like domain followed by up to three IgC2-like domains, differ mainly in membrane anchorage (CD66a is transmembrane whereas CD66c and CD66e are GPI-linked), and collectively mediate calcium-independent homophilic and heterophilic adhesion, pathogen recognition (e.g., gonococcal Opa proteins bind peptide determinants in their N-domains), neutrophil activation, and modulation of innate and adaptive immunity, apoptosis, angiogenesis, and tumor behavior.

  • 流式分析

    • Flow cytometric analysis of Human CD66a/c/e Antibody expression on human peripheral blood leukocytes. Human peripheral blood leukocytes were stained with Biotin Mouse IgG2b, k Isotype Control (left panel) or SDT Biotin Mouse Anti-Human CD66a/c/e Antibody (right panel) at 5μl/test followed by Sav-iFluor 488. Flow cytometry and data analysis were performed using Agilent NovoCyte Quanteon and FlowJo™ software.

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