热搜词：
注册
登录
CN
  • CN
  • EN

产品中心 流式试剂&相关 流式抗体

所有图片（1/1）

Mouse Anti-Human CD271 Antibody (S-2902)

Tumor necrosis factor receptor superfamily member 16,Gp80-LNGFR,Low affinity neurotrophin receptor p75NTR,Low-affinity nerve growth factor receptor (NGF receptor),Low-affinity nerve growth factor receptor p75NGFR,Low-affinity nerve growth factor receptor p75NGR,p75 ICD,TNFRSF16,NGFR

价格 ￥600.00 （ 1-2周）
货号 S0B8711
规格
数量
收藏 分享
产品介绍

产品介绍 评论(0)

产品规格

  • 宿主来源

    Mouse

  • 抗原名称

    CD271

  • 分子别名

    Tumor necrosis factor receptor superfamily member 16; Gp80-LNGFR; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor (NGF receptor); Low-affinity nerve growth factor receptor p75NGFR; Low-affinity nerve growth factor receptor p75NGR; p75 ICD; TNFRSF16; NGFR

  • 细胞定位

    Cell membrane, Synapse, Cytoplasm

  • Accession

    P08138

  • 克隆号

    S-2902

  • 抗体类型

    Mouse mAb

  • 抗体同种型

    IgG1,k

  • 反应种属 ?

    Hu

  • 阳性样本

    SW480

  • 纯化方式

    Protein G

  • 浓度

    2 mg/ml

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS pH7.4

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

  • 应用

    FCM

  • 稀释度

    应用 稀释度 推荐种属
    FCM 1:2000 Hu
背景介绍

  • CD271 (also termed p75NTR or NGFR) is a low-affinity neurotrophin receptor that functions as a context-dependent molecular switch, promoting either differentiation and apoptosis in normal tissues or survival, stemness and metastasis in cancers by activating MEK/ERK, RhoA/ROCK and other downstream cascades, and its expression marks therapy-resistant melanoma-initiating cells, drives phenotype switching in cutaneous squamous cell carcinoma, correlates with aggressive disease in medulloblastoma and neurofibromatosis tumors, and orchestrates osteogenic commitment of ectomesenchymal stem cells during craniofacial bone development.

  • 流式分析

    • Flow cytometric analysis of PC-3 (Human prostate adenocarcinoma epithelial cell, left) / SW480 (Human colorectal adenocarcinoma epithelial cell, right) labelling CD271 antibody at 1/2000 dilution (0.1 μg) / (red) compared with a Mouse monoclonal IgG (black) Isotype Control and an unlabelled control (cells without incubation with primary antibody and secondary antibody) (blue). Goat Anti - Mouse IgG Alexa Fluor® 647 was used as the secondary antibody.Flow cytometry and data analysis were performed using Agilent NovoCyte Quanteon and FlowJo™ software.
      Negative control: PC-3

评论(0)