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宿主来源
Armenian hamster抗原名称
CD36分子别名
Platelet glycoprotein 4; Glycoprotein IIIb (GPIIIB); PAS IV; PAS-4; Platelet glycoprotein IV (GPIV); Cd36细胞定位
Cell membraneAccession
Q08857克隆号
HM36抗体类型
Recombinant mAb抗体同种型
IgG反应种属 ?
Ms阳性样本
Balb/c mouse peritoneal exudates cells纯化方式
Protein G浓度
0.2 mg/ml标记
Alexa Fluor® 488性状
Liquid缓冲体系
PBS, 1% BSA, 0.3% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 5μl per million cells in 100μl volume Ms
CD36 is a heavily glycosylated 80kD integral membrane protein widely expressed on platelets, immune cells, adipocytes, myocytes, enterocytes, enteroendocrine cells, and other cell types. It is a member of the class B scavenger receptor family and functions as a pattern recognition receptor. CD36 has a diverse range of ligands and physiological functions, including the uptake of modified lipids and apoptotic cells, long-chain fatty acid transport, adhesion, and angiogenesis. It plays a role in various pathological conditions such as atherosclerosis, diabetes, and cardiomyopathy. In the gut, CD36 promotes absorption of long-chain fatty acids and participates in carotenoid uptake for vitamin A metabolism. It also acts as a receptor for thrombospondin-1 and several other proteins containing thrombospondin type I repeats, functioning as an endogenous negative regulator of angiogenesis on microvascular endothelial cells.
流式分析
Flow cytometric analysis of Mouse CD36 expression on Balb/c mouse peritoneal exudates cells. Balb/c mouse peritoneal exudates cells were stained with Brilliant Violet 421™ Rat Anti-Mouse F4/80 Antibody and either Alexa Fluor® 488 Armenian Hamster IgG Isotype Control (left panel) or SDT Alexa Fluor® 488 Armenian Hamster Anti-Mouse CD36 Antibody (right panel) at 5 μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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