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宿主来源
Armenian hamster抗原名称
TCR Vγ2细胞定位
Cell membraneAccession
A2J008克隆号
UC3-10A6抗体类型
Recombinant mAb抗体同种型
IgG反应种属 ?
Ms阳性样本
BALB/c mouse splenocytes纯化方式
Protein G浓度
0.2 mg/ml标记
FITC性状
Liquid缓冲体系
PBS, 1% BSA, 0.3% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 5μl per million cells in 100μl volume Ms
TCR Vγ2 protein is a variable-region subunit of the T-cell receptor (TCR) γ-chain that pairs with Vδ2 to form the predominant γδ TCR in human peripheral blood; this 280-residue Ig-like domain anchors to the γ-chain constant region, contacts antigen directly via surface-exposed CDR loops, and—when co-expressed with CD3 complexes—enables γδ T cells to sense phosphoantigens from microbes or stressed tumors without MHC restriction, triggering potent cytotoxicity and cytokine release that are being exploited for Vγ2/Vδ2-targeted immunotherapies against infection and cancer.
流式分析
Flow cytometric analysis of Mouse TCR Vγ2 expression on BALB/c mouse splenocytes. BALB/c mouse splenocytes were stained with Brilliant Violet 421™ Rat Anti-Mouse CD3 antibody and either FITC Armenian hamster IgG Isotype Control (Left panel) or SDT FITC Armenian hamster Anti-Mouse TCR Vγ2 Antibody (Right panel) at 5 μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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