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宿主来源
Mouse抗原名称
CD235a分子别名
Glycophorin-A; MN sialoglycoprotein; PAS-2; Sialoglycoprotein alpha; GPA; MNS; GYPA细胞定位
Cell membraneAccession
P02724克隆号
NNA7抗体类型
Mouse mAb抗体同种型
IgG2a,k反应种属 ?
Hu阳性样本
Human Peripheral Blood cells纯化方式
Protein A浓度
0.2 mg/ml标记
Alexa Fluor® 647性状
Liquid缓冲体系
PBS, 1% BSA, 0.3% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 1.25μl per million cells in 100μl volume Hu
CD235a protein, also known as Glycophorin A, is a major intrinsic membrane protein of human red blood cells and erythroid precursor cells. It is a type I sialoglycoprotein with a molecular weight of around 10 kD, present in the cell membrane as a homodimer. This protein serves as a carrier for the MN blood group antigens. It also plays a crucial role in maintaining the integrity and shape of the erythrocyte membrane by being a part of the ankyrin-1 complex. Additionally, CD235a acts as a receptor for several pathogens, including the influenza virus, Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175), and hepatitis A virus.
流式分析
Flow cytometric analysis of Human CD235a expression on Human Peripheral Blood cells. Human Peripheral Blood cells were stained with PE-Cy7 Mouse Anti-Human CD45 Antibody and either Alexa Fluor® 647 Mouse IgG2a, κ Isotype Control (Left panel) or Alexa Fluor® 647 Mouse Anti-Human CD235a Antibody (Right panel) at 1.25 μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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