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宿主来源
Rat抗原名称
CD31分子别名
Platelet endothelial cell adhesion molecule; PECAM-1; Pecam; Pecam1细胞定位
Cell membraneAccession
Q08481克隆号
MEC13.3抗体类型
Rat mAb抗体同种型
IgG2a,k反应种属 ?
Ms阳性样本
C57BL/6 mouse splenocytes纯化方式
Protein G浓度
0.2 mg/ml标记
Biotin性状
Liquid缓冲体系
PBS pH7.4, 0.03% Proclin 300
储存条件
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
应用
FCM
稀释度
应用 稀释度 推荐种属 FCM 5μl per million cells in 100μl volume Ms
CD31, also known as platelet endothelial cell adhesion molecule (PECAM-1), is a glycoprotein encoded by the PECAM1 gene and expressed on endothelial cells, platelets, and various types of leukocytes. It is a type I transmembrane protein with six extracellular immunoglobulin-like domains, a transmembrane segment, and a short cytoplasmic tail. CD31 plays crucial roles in cell-cell adhesion, immune response, and vascular integrity. It facilitates leukocyte transmigration during inflammation, maintains endothelial cell junctions, and regulates vascular permeability. Additionally, CD31 is involved in angiogenesis and has potential implications in cancer metastasis and thrombus formation. Its expression and function are also implicated in various diseases, including atherosclerosis and Alzheimer's disease.
流式分析
Flow cytometric analysis of Mouse CD31 expression on C57BL/6 mouse splenocytes. C57BL/6 mouse splenocytes were stained with Pacific Blue Rat Anti-Mouse CD45R/B220 antibody and either Biotin Rat IgG2a, κ Isotype Control (Left panel) or SDT Biotin Rat Anti- Mouse CD31 antibody (Right panel) at 5 μl/test followed by Sav-PE. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
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