热搜词：
注册
登录
CN
  • CN
  • EN

产品中心 流式试剂&相关 流式抗体

所有图片（1/1）

Rat Anti-Mouse CD122 (IL-2Rβ) Antibody (TM-β1)

Interleukin-2 receptor subunit beta,IL-2 receptor subunit beta,IL-2R subunit beta,IL-2RB,High affinity IL-2 receptor subunit beta,p70-75,Il2rb

价格 ￥600.00 （ 1-2周）
货号 S0B8525
规格
数量
收藏 分享
产品介绍

产品介绍 评论(0)

产品规格

  • 宿主来源

    Rat

  • 抗原名称

    CD122 (IL-2Rβ)

  • 分子别名

    Interleukin-2 receptor subunit beta; IL-2 receptor subunit beta; IL-2R subunit beta; IL-2RB; High affinity IL-2 receptor subunit beta; p70-75; Il2rb

  • 细胞定位

    Cell membrane

  • Accession

    P16297

  • 克隆号

    TM-β1

  • 抗体类型

    Rat mAb

  • 抗体同种型

    IgG2b,k

  • 反应种属 ?

    Ms

  • 阳性样本

    C57BL/6 mouse splenocytes

  • 纯化方式

    Protein G

  • 浓度

    2 mg/ml

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS pH7.4

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

  • 应用

    FCM

  • 稀释度

    应用 稀释度 推荐种属
    FCM 1:200 Ms
背景介绍

  • CD122, also known as interleukin-2 receptor beta (IL-2Rβ), is a 75 kDa type I transmembrane glycoprotein that serves as the shared signaling subunit for the IL-2, IL-7 and IL-15 cytokine receptors; upon ligand binding it heterodimerizes with IL-2Rγc to activate JAK1/JAK3–STAT5, PI3K–AKT and MAPK pathways that drive survival, proliferation and cytolytic programs in T, B, NK and memory T cells, making it a central regulator of both lymphocyte homeostasis and potent target for immunotherapies against cancer and autoimmunity.

  • 流式分析

    • Flow cytometric analysis of C57BL/6 mouse splenocytes labelling Mouse CD122 (IL-2Rβ) antibody at 1/200 dilution (1 μg) / (Right panel) compared with a Rat IgG2b, κ Isotype Control / (Left panel). Goat Anti-Rat IgG Alexa Fluor® 488 was used as the secondary antibody. Then cells were stained with CD49b – APC Antibody separately.

评论(0)