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产品中心 流式试剂&相关 流式抗体

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Mouse Anti-Human CD54 Antibody (S-3807)

Intercellular adhesion molecule 1,ICAM-1,Major group rhinovirus receptor,ICAM1

价格 ￥600.00 （ 1-2周）
货号 S0B8456
规格
数量
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产品介绍

产品介绍 评论(0)

产品规格

  • 宿主来源

    Mouse

  • 抗原名称

    CD54

  • 分子别名

    Intercellular adhesion molecule 1; ICAM-1; Major group rhinovirus receptor; ICAM1

  • 细胞定位

    Membrane

  • Accession

    P05362

  • 克隆号

    S-3807

  • 抗体类型

    Mouse mAb

  • 抗体同种型

    IgG2a

  • 反应种属 ?

    Hu

  • 阳性样本

    human peripheral blood leukocytes

  • 纯化方式

    Protein A

  • 浓度

    2 mg/ml

  • 标记

    Unconjugated

  • 性状

    Liquid

  • 缓冲体系

    PBS pH7.4

  • 储存条件

    12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

  • 应用

    FCM

  • 稀释度

    应用 稀释度 推荐种属
    FCM 1:200 Hu
背景介绍

  • CD54 is an 85–110 kDa transmembrane glycoprotein of the immunoglobulin superfamily that is expressed on endothelial, epithelial and immune cells; upon binding its ligands LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18) it serves as the critical adhesion checkpoint that promotes firm leukocyte arrest on the vessel wall, enables subsequent diapedesis into inflamed tissue, and amplifies antigen-specific T-cell activation, thereby positioning it at the mechanistic center of inflammatory, autoimmune and anti-tumor immune responses.

  • 流式分析

    • Flow cytometric analysis of human peripheral blood leukocytes labelling Human CD54 antibody at 1/200 dilution (1 μg) / (Right panel) compared with a Mouse IgG2a Isotype Control / (Left panel). Goat Anti-Mouse IgG Alexa Fluor® 647 was used as the secondary antibody.

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